The Dutch word handschrift has two meanings: handwriting and manuscript.
The further we go back, the more difficult it is to get samples of our ancestors’ handwriting, or know if they even could read and write. After 1811, civil registration birth, marriage, and death records include signatures of the parties, or a statement that they couldn’t write. Before 1811, notarial or voluntary court records are a good place to look for signatures.
Manuscripts are records that are hand-written. They can often be found at libraries or archives.